Genetic variants associated with disordered eating
نویسندگان
چکیده
منابع مشابه
Genetic variants associated with disordered eating.
OBJECTIVE Although the genetic contribution to the development of anorexia nervosa (AN) has long been recognized, there has been little progress relative to other psychiatric disorders in identifying specific susceptibility genes. Here, we have carried out a genome-wide association study on an unselected community sample of female twins surveyed for eating disorders. METHOD We conducted genom...
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OBJECTIVE Eating disorders develop through a combination of genetic vulnerability and environmental stress, however the genetic basis of this risk is unknown. METHODS To understand the genetic basis of this risk, we performed whole exome sequencing on 93 unrelated individuals with eating disorders (38 restricted-eating and 55 binge-eating) to identify novel damaging variants. Candidate genes ...
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BACKGROUND Previous research suggests that genetic influences on disordered eating may be greater in pubertal than pre-pubertal girls. Although these findings are consistent with pubertal activation of genetic influences on disordered eating, earlier studies were unable to directly test this hypothesis. The purpose of the present study therefore was to directly examine this possibility by inves...
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OBJECTIVES The current study sought to compare different features of unhealthy exercise on associations with disordered eating and their ability to identify individuals with eating disorders. A secondary aim of the study was to compare prevalence and overlap of different aspects of unhealthy exercise and potential differences in their gender distribution. DESIGN Cross-sectional epidemiologica...
متن کاملGenetic Variants Associated with Colorectal Adenoma Susceptibility
BACKGROUND Common low-penetrance genetic variants have been consistently associated with colorectal cancer risk. AIM To determine if these genetic variants are associated also with adenoma susceptibility and may improve selection of patients with increased risk for advanced adenomas and/or multiplicity (≥ 3 adenomas). METHODS We selected 1,326 patients with increased risk for advanced adeno...
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ژورنال
عنوان ژورنال: International Journal of Eating Disorders
سال: 2013
ISSN: 0276-3478
DOI: 10.1002/eat.22133